Microsphere antioxidant and sustained erythropoietin-R76E release functions cooperate to reduce traumatic optic neuropathy
نویسندگان
چکیده
منابع مشابه
Traumatic ischaemic optic neuropathy.
Persistent profound visual loss following contusion of the globe or ocular adnexae has been well documented, the visual loss being attributed to haemorrhage into, or contusion of, the optic nerve, or to interference with the blood supply of the eye. The patient described below presented after a contusion of the eye and orbit, with the clinical picture of ischaemic optic neuropathy presumably re...
متن کاملIndirect traumatic optic neuropathy
Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury, such as from sports- or motor vehicle-related concu...
متن کاملTraumatic optic neuropathy.
Introduction: Traumatic optic nerve damage after craniofacial injury was first described by Hippocrates.1 Although the natural history of traumatic optic neuropathy is unknown, recent studies suggest that high dose steroids and, even surgical decompression of the optic canal or the nerve sheath (in cases of nerve sheath hematoma) may restore vision in selected patients.2-8 The commonest cause o...
متن کاملHow to manage traumatic optic neuropathy?
In this issue of the Taiwan Journal of Ophthalmology, a review article on traumatic optic neuropathy by Dr Patrick Yu-Wai-Man1 is included. The article reviews the clinical features and current evidence of treatment for traumatic optic neuropathy. The controversy surrounding the use of steroid in the management of traumatic optic neuropathy has been a matter of debate over a long period. Dr Pat...
متن کاملTraumatic optic neuropathy--to treat or not to treat?
CASE REPORTS We present two cases of blunt ocular trauma with clinical findings and complementary tests compatible with traumatic optic neuropathy (TON), and progression to sectorial optic atrophy. DISCUSSION TON have an essentially clinical diagnosis, and in the last few years has been treated with high doses of intravenous steroids, based on weak evidence of the benefit of the steroids in c...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2021
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2020.10.010